Dr. Munné gained his Ph.D. in Genetics from the University of Pittsburgh and joined Dr. Jacques Cohen at Cornell University Medical College (NY), where he developed the first Preimplantation Genetic Testing (PGT) method to detect chromosome abnormalities (1993), for which he received prizes in 1994 and 1995 by SART. Dr. Munné became the Director of PGT at The Institute for Reproductive Medicine and Science of Saint Barnabas in 1995 where he developed the first test to detect chromosome translocations (1996 SART prize), as well as demonstrating a significant decrease in spontaneous abortions after PGT (1998 SART prize). His team and collaborators were the first to suggest and demonstrate higher implantation rates, lower rates of spontaneous abortions as well as trisomic offspring after PGT.
In 2001, Dr. Munné co-founded Reprogenetics, with Jacques Cohen and David Sable. He directed the company until 2016 and saw its expansion to four continents. Reprogenetics was the first US commercial PGT lab and the market leader until it was sold to in 2016 to Cooper Companies (NYSE: COO). During this time Reprogenetics performed over 70,000 PGT cycles and its research focused in using comprehensive genetic analysis of embryos to improve pregnancy outcomes and diminish the risk of miscarriages and inherited disorders. Munné and co-researchers were rewarded with SART prize papers in 2005, 2015 and 2016, and he has received The ASRM Star Award consecutively for the years 2011-2017.
In 2011 Dr. Munné co-founded with Alex Bisignano the genomics company, Recombine offering Carrier screening for over 300 genes. Part of the company was sold in 2016 also to Cooper Companies (NYSE: COO), and the rest spun off as Phosphorous, a genomics company co-founded by Dr. Munné and Alex Bisignano, which recently launched a comprehensive germ-line panel of 400 genes (Phosphorus-One). In addition, in 2017 Dr. Munné co-founded MedAnswers with CEO Alice Crisci, an infertility digital health platform connecting patients with specialists. With the CooperSurgical purchase of Reprogenetics, Recombine and Genesis Genetics, in 10/2016 Dr. Munné’s became the Chief Scientific Officer of CooperGenomics, titled that he held until Dec 2017 when he joined with Martin Varsavsky and Joson Horcajadas to co-found Overture Life, a company focused on automating the ART Laboratory. He is also an adjunct professor at Yale University Dept of Ob/Gyn and Reprod Sci., and is founder of HoMu, a company accelerator focused on early stage biomedical research.
Current research interests are the prevention of genetic disease and infertility through PGT, Carrier and germ-line Screening, to reduce chromosome abnormalities in embryos by changing assisted reproductive methods, detection of de novo mutations in embryos inducing autism and other disorders, and non-invasive PGT. Dr. Munné has published over 260 peer-reviewed scientific publications, and is a frequent lecturer, both nationally and internationally. He is co-founder of the Preimplantation Genetic Diagnosis International Society (PGDIS) and has served as president and BOD.