Shoukhrat Mitalipov, Ph.D., directs the Center for Embryonic and Gene Therapy at Oregon Health & Science University. His research is focused on investigating and developing novel germline cell and gene therapy approaches for treatment of infertility and for preventing the transmission of genetic diseases from parents to children.

Dr. Mitalipov’s team pioneered the concept of mitochondrial replacement therapy to prevent transmission of mtDNA defects from mothers to children. More recently, Dr. Mitalipov and his colleagues demonstrated that gene-editing tools can be effectively used to repair heterozygous nuclear DNA mutations in human embryos.